奚菊群,女,博士,讲师。2003年6月毕业于
扬州大学化学化工学院,同年保送至本校攻读化学化工学院物理化学专业博士学位
www.med126.com,开展纳米胶束和纳米脂质体等药物载体方面的研究。2008年6月获得博士学位,同年7月至扬州大学医学院药学系工作,从事药剂学的教学与科研工作。目前主要从事基于纳米技术的新型药物输送系统设计、构建与表征。主要研究内容包括采用高分子材料学、生物材料学及有机合成化学等的方法和原理
www.med126.com,通过分子设计、改性和修饰等技术合成可生物降解、安全的相关纳米材料,包括多糖类高分子、功能化两亲性高分子、脂质材料和无机纳米材料等,并对其性状、结构、生物物理特性、载药与药物释放特性、特异性的纳米效应等进行表征。
发表的研究论文:
(1) Juqun Xi, Rong Guo, Xia Guo, Interactions of hemoglobin with lecithin liposomes, Colloid Polym. Sci. 2006 (284) 1139-1145
(2) Juqun Xi, Rong Guo, Interactions between flavonoids and hemoglobin in lecithin liposomes, Int. Biol. Macromol. 2007 (40) 305-311.
(3) Juqun Xi, Rong Guo, Acid–base equilibrium of puerarin in CTAB micelles, J. Pharmaceut. Biomed. 2007 (43) 111-118.
(4) Juqun Xi, Rong Guo, Studies on molecular interactions between puerarin and PC liposomes, Chinese Sci. Bull. 2007 (52) 2612-2617.
(5) Juqun Xi, Rong Guo, Interactions of puerarin with micelles: pKa shifts and thermodynamics, J. of Solution Chem. 2008 (37) 107-118.
(6) Juqun Xi, Rong Guo, Effects of pH and micelle on the radical scavenging ability of puerarin, J. Disper. Sci. Technol. 2009 (30) 857-864.
(7) Juqun Xi, Rong Guo, Studies on the interactions between genistein and copolymer F127, J. Solution Chem. 2009 (38) 1588-1600.
(8) Yongsheng Wang, Rong Guo, Juqun Xi, Comparative studies of interactions of hemoglobin with single-chain and with gemini surfactants, J. Colloid Interf. Sci. 2009(331)470– 475.
(9)Juqun Xi, Lei Fan, Study on the binding of puerarin to bovine serum albumin by isothermal titration calorimetry and spectroscopic approaches, J. Therm. Anal. Calorim. 2010 (102)217–223.