代表
论著;
1) Igor Klyubin , Qinwen Wang* , Miranda N. Reed, Elaine A. Irving, Neil Upton, Jacki Hofmeisteri, James P. Cleary , Roger Anwy , Michael J. Rowan. Protection against Aß-mediated rapid disruption of synaptic plasticity and memory by memantine. Neurobiology of aging, 2009 May 13. Epub ahead of print.(*equal contribution)
2) Chu-Li Yi, Yu-Wei Liu, Ke-Ming Xiong , Randall R. Stewart, Robert W. Peoples, Xiang Tian a, Li Zhou, Yong-Xun Ai , Zhi-Wang Lia, Qin-Weng Wang*, Chao-Ying Li, Conserved extracellular cysteines differentially regulate the inhibitory effect of ethanol in rat P2X4 receptors. Biochemical and Biophysical Research Communications,2009,381(1),102-106(*CA)
3) Michael J. Rowan, Igor. Klyubin Qinwen Wang Nengwei Hu and Roger Anwyl.Synaptic memory mechanisms: Alzheimer’s disease amyloid β-peptide-induced dysfunction. Biochem Soc Trans. 2007,11,1219-1223.
4) Kotilinek LA, Westerman MA, Wang Q, Panizzon K, Lim GP, Simonyi A, Lesne S, Falinska A, Younkin LH, Younkin SG, Rowan M, Cleary J, Wallis RA, Sun GY, Cole G, Frautschy S, Anwyl R, Ashe KH(*equal contribution) Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity. Brain 2008,131:651-664。
5) Qin-wen Wang, Michael J Rowan and Roger Anwyl Inhibition of LTP by beta-amyloid is prevented by activation of beta2 adrenoceptors and stimulation of cAMP/PKA Neurobiology of aging. 2008,2, Epub ahead of print。
6) Qinwen Wang, Igor Klyubin, Sarah Wright, Irene Griswold-Prenner, Michael Rowan and Roger Anwyl. αVβ1 integrin mediate beta-amyloid induced inhibition of long-term potentiation Neurobiology of aging。2008, 29(10):1485-93.
7) Qinwen Wang, Lan chang, Michael J. Rowan and Roger Anwyl. Developmental dependence, the role of the kinases p38 MAPK and PKC and the involvement of tumor necrosis factor-R1 in the induction of mGlu-5 LTD in the dentate gyrus. Neuroscience 2007,144(1):110-8
8) Qinwen Wang, Jinqun Wu, Michael J. Rowan and Roger Anwyl. beta-amyloid inhibition of LTP is mediated via tumor necrosis factor. Eu Jb The Neuroscience. 2005 ;22(11):2827-32.
www.med126.com9) Michael J. Rowan, Igor. Klyubin, Qinwen Wang and Roger Anwyl. Synaptic plasticity disruption by amyloid beta protein: modulation by potential Alzheimer's disease modifying therapies. Biochem Soc Trans. 2005 8; 33 : 563-7
10) Michael J. Rowan, Igor. Klyubin, Qinwen Wang and Roger Anwy. Mechanisms of the inhibitory effects of amyloid beta-protein on synaptic plasticity .Exp Gerontol. 2004 11-12; 39(11-12):1661-7
11) Qinwen Wang, Dominic M. Walsh, Michael J. Rowan, Dennis J. Selkoe and Roger Anwyl . Block of LTP by naturally secreted and synthetic amyloid b-peptide in hippocampal slices is mediated via activation of the kinases JNK, Cdk5 and p38 MAPK, and metabotropic glutamate receptor 5. J Neurosci. 2004, 24(13):3370-8.
12) Qinwen Wang, Michael J. Rowan and Roger Anwyl. β-Amyloid-mediated inhibition of LTP induction involves activation of microglia and stimulation of inducible nitric oxide synthase, superoxide, NADPH. J Neurosci. 2004, 24(27):6049-6056
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