近

五

年

发

表

论

文

代

表

作

1. Wu GQ, Li LX, wang HL, et al. The activity of thanatin analog(S-thanatin) on clinical isolates of Klebsiella pneumoniae resistant to conventional antibiotics with different structures. Curr Microbiol DOI 10.1007/s00284-009-9410-2.

2. Liu NF, Wu GQ*, Xing HL, et al. A novel peptide isolated from a phage display peptides library recognized by an antibody against connective tissue growth factor(CTGF). Int Immunopharmacol, 2009, 9: 291-297 (*equally contribute to this work).

3. Wu GQ, Li LX, Ding JX, et al. High-Level Expression and Novel Purification Strategy of Recombinant Thanatin Analog in Escherichia coli. Curr Microbiol, 2008, 57: 95–101.

4. Wu GQ, Ding JX, Li H, et al. Effects of Cations and PH on Antimicrobial Activity of Ts and s-Thanatin Against Escherichia coli ATCC25922 and B. subtilis ATCC 21332. Curr Microbiol, 2008, 57: 552-557.

5. Wu GQ, Liu NF, Li LX, et al. Level of connective tissue growth factor in sera of patients with virus hepatitis B highly correlated with stage of hepatic fibrosis. Hepatol Res, 2008(HEPRES-08-0349‏).

6. Cirioni O, Wu GQ*, Li L, et al. Thanatin enhances the efficacy of tigecycline in an experimental rat model www.med126.com of polymicrobial peritonitis. Antimicrob Agents Chemother, 2009 (AAC-09-0817)(*equally contribute to this work).

7. Wu GQ, Li LX, Wang HL, et al. Interaction of Antimicrobial Peptide S-Thanatin with Lipopolysaccharide In Vitro and in Experimental Mouse Models of Septic Shock Caused by Multidrug-resistant clinical isolate of Escherichia coli. Curr Microbiol, 2008(CM-08-00656).

8. Liu BC, Zhang JD, Wu GQ, et al. Role of connective tissue growth factor (CTGF) module 4 in regulating epithelial mesenchymal transition (EMT) in HK-2 cells. Clinica Chimica Acta, 2006, 373, 144–150.

近五年

获得

专利

1. 吴国球. 与整合素αvβ3具有高结合活性的多肽及其应用(申请号: 200910025731.0 ).

2. 沈子龙, 吴国球. 一种昆虫抗菌肽thanatin及其缺失突变体的制备方法(公开号：CN10117300).

3. 沈子龙, 吴国球. 昆虫抗菌肽thanatin衍生物及其制备方法和用途(公开号：CN101173005).

4. 刘乃丰, 吴国球. 结缔组织生长因子C区抗原制备方法(授权号:ZL200310112672.3).

5. 沈子龙, 吴国球. 利用噬菌体展示技术展示抗原制备抗体的方法(授权号:ZL03131796.0).

6. 沈子龙, 吴国球. 心肌肌钙蛋白鲁米诺化学发光免疫分析检测方法(授权号:ZL03131797.9).